AZABICYCLOALKANES AS ANALGETICS .3. STRUCTURE-ACTIVITY-RELATIONSHIPS OF "1-PHENYL-6-AZABICYCLO[3.2.1]OCTANES AND ABSOLUTE STEREOCHEMISTRY OF (+)-1-(3-HYDROXYPHENYL)-6-METHYL-6-AZABICYCLO[3.2.1]OCTANE AND IS 7-ENDO-METHYL DERIVATIVE

被引：23

作者：

TAKEDA, M ^{[1
]}

INOUE, H ^{[1
]}

NOGUCHI, K ^{[1
]}

HONMA, Y ^{[1
]}

KAWAMORI, M ^{[1
]}

TSUKAMOTO, G ^{[1
]}

YAMAWAKI, Y ^{[1
]}

SAITO, S ^{[1
]}

AOE, K ^{[1
]}

DATE, T ^{[1
]}

NURIMOTO, S ^{[1
]}

HAYASHI, G ^{[1
]}

机构：

[1] TANABE SEIYAKU CO LTD,RES LABS,TODA,SAITAMA,JAPAN

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1977年 / 20卷 / 02期

关键词：

D O I：

10.1021/jm00212a007

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：221 / 228

页数：8

共 47 条

[1]

ACETO MD, 1975, 37TH M COMM PROBL DR

[2] SEPARATION OF MORPHINE-LIKE EFFECTS BY OPTICAL RESOLUTION . LEVO ISOMERS AS STRONG ANALGETICS AND NARCOTIC ANTAGONISTS [J].

AGER, JH ;

JACOBSON, AE ;

MAY, EL .

JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (02) :288-&

[3]

ARCHER S, 1965, PROGR DRUG RES, V8, P261

[4] IMPORTANCE OF NITROGEN LONE ELECTRON PAIR ORIENTATION IN STEREOSPECIFIC OPIATES [J].

BELLEAU, B ;

CONWAY, T ;

AHMED, FR ;

HARDY, AD .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (08) :907-908

[5] DETERMINATION OF THE ABSOLUTE CONFIGURATION OF OPTICALLY ACTIVE COMPOUNDS BY MEANS OF X-RAYS [J].

BIJVOET, JM ;

PEERDEMAN, AF ;

VANBOMMEL, AJ .

NATURE, 1951, 168 (4268) :271-272

[6]

BOWMAN RE, 1969, CHEM IND-LONDON, P1077

[7] ABSOLUTE CONFIGURATION OF SOME BENZOMORPHAN ANALGETICS AND RELATED COMPOUNDS [J].

CASY, AF ;

PARULKAR, AP .

JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (01) :178-&

[8] OXYDATION DE QUELQUES AMINES TERTIAIRES PAR LANHYDRIDE CHROMIQUE DANS LA PYRIDINE [J].

CAVE, A ;

KANFAN, C ;

POTIER, P ;

LEMEN, J ;

JANOT, MM .

TETRAHEDRON, 1967, 23 (12) :4691-&

[9]

CHRISTEN.JA, 1965, ACTA PHARMACOL TOX, V23, P109

[10]

CLARKE FH, 1974, ADV BIOCH PSYCHOPHAR, V8, P81

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