ACQUIRED METHOTREXATE RESISTANCE IN LYMPHOBLASTS RESULTING FROM ALTERED KINETIC-PROPERTIES OF DIHYDROFOLTATE REDUCTASE

被引：91

作者：

JACKSON, RC

NIETHAMMER, D

机构：

[1] INDIANA UNIV,EXPT ONCOL LAB,INDIANAPOLIS,IN 46202

[2] UNIV ULM,DEPT PAEDIAT,D-7900 ULM,FED REP GER

来源：

EUROPEAN JOURNAL OF CANCER | 1977年 / 13卷 / 06期

关键词：

D O I：

10.1016/0014-2964(77)90118-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：567 / 575

页数：9

共 35 条

[1]

BLUMENTHAL G, 1970, Oncology (Basel), V24, P223

[2]

BORSA J, 1969, MOL PHARMACOL, V5, P318

[3]

BRUCKNER H, 1976, P AM ASSOC CANC RES, V17, P158

[4] COMPUTER PROGRAMMES FOR PROCESSING ENZYME KINETIC DATA [J].

CLELAND, WW .

NATURE, 1963, 198 (487) :463-+

[5] DISC ELECTROPHORESIS .2. METHOD AND APPLICATION TO HUMAN SERUM PROTEINS [J].

DAVIS, BJ .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1964, 121 (A2) :404-&

[6] INTERCONVERSION OF MULTIPLE FORMS OF DIHYDROFOLATE REDUCTASE FROM AMETHOPTERIN-RESISTANT LACTOBACILLUS-CASEI [J].

DUNLAP, RB ;

GUNDERSEN, LE ;

HUENNEKENS, FM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1971, 42 (05) :772-+

[7] The mechanism of enzyme-inhibitor-substrate reactions [J].

Goldstein, A .

JOURNAL OF GENERAL PHYSIOLOGY, 1944, 27 (06) :529-580

[8]

HAKALA MT, 1961, J BIOL CHEM, V236, P962

[9]

HARRAP KR, 1971, ANN NY ACAD SCI, V186, P312

[10] STEADY-STATE ENZYME-KINETICS WITH HIGH-AFFINITY SUBSTRATES OR INHIBITORS - STATISTICAL TREATMENT OF DOSE-RESPONSE CURVES [J].

HENDERSON, PJ .

BIOCHEMICAL JOURNAL, 1973, 135 (01) :101-107

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