STRUCTURE AND STEREOCHEMISTRY OF MULTICOLANIC, MULTICOLIC, AND MULTICOLOSIC ACIDS, 4-YLIDENETETRONIC ACID METABOLITES FROM PENICILLIUM-MULTICOLOR - SYNTHESIS OF METHYL (E)-O-METHYLMULTICOLANATE

被引：16

作者：

GEDGE, DR ^{[1
]}

PATTENDEN, G ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT CHEM,NOTTINGHAM NG7 2RD,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1979年 / 01期

关键词：

D O I：

10.1039/p19790000089

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The application of 2-methoxy-3-n-pentylmaleic anhydride (8) in the synthesis of methyl O-methylmulticolanate (9) and its geometrical isomer is described. Comparison of 1H and 13C n.m.r. data with those of the dimethyl derivative of natural multicolanic acid (1a) from Penicillium multicolor establishes an E-geometry for (1a), and for the related multicolic (1b) and multicolosic acids (1c). The alternative bis-butenolide formulation (11) is entertained for the ylidenetetronic acids.

引用

页码：89 / 91

页数：3

共 14 条

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