An official American Thoracic Society/European Respiratory Society statement: research questions in COPD

被引：73

作者：

Celli, Bartolome R. ^{[1
]}

Decramer, Marc ^{[1
]}

Wedzicha, Jadwiga A. ^{[1
]}

Wilson, Kevin C. ^{[1
]}

Agusti, Alvar A. ^{[1
]}

Criner, Gerard J. ^{[1
]}

MacNee, William ^{[1
]}

Make, Barry J. ^{[1
]}

Rennard, Stephen I. ^{[1
]}

Stockley, Robert A. ^{[1
]}

Vogelmeier, Claus ^{[1
]}

Anzueto, Antonio ^{[1
]}

Au, David H. ^{[1
]}

Barnes, Peter J. ^{[1
]}

Burgel, Pierre-Regis ^{[1
]}

Calverley, Peter M. ^{[1
]}

Casanova, Ciro ^{[1
]}

Clini, Enrico M. ^{[1
]}

Cooper, Christopher B. ^{[1
]}

Coxson, Harvey O. ^{[1
]}

Dusser, Daniel J. ^{[1
]}

Fabbri, Leonardo M. ^{[1
]}

Fahy, Bonnie ^{[1
]}

Ferguson, Gary T. ^{[1
]}

Fisher, Andrew ^{[1
]}

Fletcher, Monica J. ^{[1
]}

Hayot, Maurice ^{[1
]}

Hurst, John R. ^{[1
]}

Jones, Paul W. ^{[1
]}

Mahler, Donald A. ^{[1
]}

Maltais, Francois ^{[1
]}

Mannino, David M. ^{[1
]}

Martinez, Fernando J. ^{[1
]}

Miravitlles, Marc ^{[1
]}

Meek, Paula M. ^{[1
]}

Papi, Alberto ^{[1
]}

Rabe, Klaus F. ^{[1
]}

Roche, Nicolas ^{[1
]}

Sciurba, Frank C. ^{[1
]}

Sethi, Sanjay ^{[1
]}

Siafakas, Nikos ^{[1
]}

Sin, Don D. ^{[1
]}

Soriano, Joan B. ^{[1
]}

Stoller, James K. ^{[1
]}

Tashkin, Donald P. ^{[1
]}

Troosters, Thierry ^{[1
]}

Verleden, Geert M. ^{[1
]}

Verschakelen, Johny ^{[1
]}

Vestbo, Jorgen ^{[1
]}

Walsh, John W. ^{[1
]}

机构：

[1] Boston Univ, Med Ctr, Amer Thorac Soc Pulm Ctr, Documents & Med Affairs, R 304,72 E Concord St, Boston, MA 02118 USA

来源：

EUROPEAN RESPIRATORY REVIEW | 2015年 / 24卷 / 136期

关键词：

D O I：

10.1183/16000617.00000315

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality and resource use worldwide. The goal of this official American Thoracic Society (ATS)/European Respiratory Society (ERS) Research Statement is to describe evidence related to diagnosis, assessment, and management; identify gaps in knowledge; and make recommendations for future research. It is not intended to provide clinical practice recommendations on COPD diagnosis and management. Clinicians, researchers and patient advocates with expertise in COPD were invited to participate. A literature search of Medline was performed, and studies deemed relevant were selected. The search was not a systematic review of the evidence. Existing evidence was appraised and summarised, and then salient knowledge gaps were identified. Recommendations for research that addresses important gaps in the evidence in all areas of COPD were formulated via discussion and consensus. Great strides have been made in the diagnosis, assessment and management of COPD, as well as understanding its pathogenesis. Despite this, many important questions remain unanswered. This ATS/ERS research statement highlights the types of research that leading clinicians, researchers and patient advocates believe will have the greatest impact on patient- centred outcomes.

引用

页码：159 / 172

页数：14

共 121 条

[1]

Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease - A randomized trial [J].

Aaron, Shawn D. ;

Vandemheen, Katherine L. ;

Fergusson, Dean ;

Maltais, Francois ;

Bourbeau, Jean ;

Goldstein, Roger ;

Balter, Meyer ;

O'Donnell, Denis ;

McIvor, Andrew ;

Sharma, Sat ;

Bishop, Graham ;

Anthony, John ;

Cowie, Robert ;

Field, Stephen ;

Hirsch, Andrew ;

Hernandez, Paul ;

Rivington, Robert ;

Road, Jeremy ;

Hoffstein, Victor ;

Hodder, Richard ;

Marciniuk, Darcy ;

McCormack, David ;

Fox, George ;

Cox, Gerard ;

Prins, Henry B. ;

Ford, Gordon ;

Bleskie, Dominique ;

Doucette, Steve ;

Mayers, Irvin ;

Chapman, Kenneth ;

Zamel, Noe ;

FitzGerald, Mark .

ANNALS OF INTERNAL MEDICINE, 2007, 146 (08) :545-U15

[2]

Lungs, Bone Marrow, and Adipose Tissue A Network Approach to the Pathobiology of Chronic Obstructive Pulmonary Disease [J].

Agusti, Alvar ;

Barbera, Joan A. ;

Wouters, Emiel F. M. ;

Peinado, Victor I. ;

Jeffery, Peter K. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 188 (12) :1396-1406

[3]

Short- and Medium-term Prognosis in Patients Hospitalized for COPD Exacerbation The CODEX Index [J].

Almagro, Pedro ;

Soriano, Joan B. ;

Cabrera, Francisco J. ;

Boixeda, Ramon ;

Alonso-Ortiz, M. Belen ;

Barreiro, Bienvenido ;

Diez-Manglano, Jesus ;

Murio, Cristina ;

Heredia, Josep L. .

CHEST, 2014, 145 (05) :972-980

[4]

[Anonymous], 1980, Ann Intern Med, V93, P391

[5]

PROGNOSIS IN CHRONIC OBSTRUCTIVE PULMONARY-DISEASE [J].

ANTHONISEN, NR ;

WRIGHT, EC ;

HODGKIN, JE ;

HOPEWELL, PC ;

LEVIN, DC ;

STEVENS, PM .

AMERICAN REVIEW OF RESPIRATORY DISEASE, 1986, 133 (01) :14-20

[6]

Smoking and lung function of lung health study participants after 11 years [J].

Anthonisen, NR ;

Connett, JE ;

Murray, RP .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 166 (05) :675-679

[7]

A Combined Pulmonary-Radiology Workshop for Visual Evaluation of COPD: Study Design, Chest CT Findings and Concordance with Quantitative Evaluation [J].

Barr, R. Graham ;

Berkowitz, Eugene A. ;

Bigazzi, Francesca ;

Bode, Frederick ;

Bon, Jessica ;

Bowler, Russell P. ;

Chiles, Caroline ;

Crapo, James D. ;

Criner, Gerard J. ;

Curtis, Jeffrey L. ;

Dass, Chandra ;

Dirksen, Asger ;

Dransfield, Mark T. ;

Edula, Goutham ;

Erikkson, Leif ;

Friedlander, Adam ;

Galperin-Aizenberg, Maya ;

Gefter, Warren B. ;

Gierada, David S. ;

Grenier, Philippe A. ;

Goldin, Jonathan ;

Han, MeiLan K. ;

Hanania, Nicola A. ;

Hansel, Nadia N. ;

Jacobson, Francine L. ;

Kauczor, Hans-Ulrich ;

Kinnula, Vuokko L. ;

Lipson, David A. ;

Lynch, David A. ;

MacNee, William ;

Make, Barry J. ;

Mamary, A. James ;

Mann, Howard ;

Marchetti, Nathaniel ;

Mascalchi, Mario ;

McLennan, Geoffrey ;

Murphy, James R. ;

Naidich, David ;

Nath, Hrudaya ;

Newell, John D., Jr. ;

Pistolesi, Massimo ;

Regan, Elizabeth A. ;

Reilly, John J. ;

Sandhaus, Robert ;

Schroeder, Joyce D. ;

Sciurba, Frank ;

Shaker, Saher ;

Sharafkhaneh, Amir ;

Silverman, Edwin K. ;

Steiner, Robert M. .

COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2012, 9 (02) :151-159

[8]

Smokers with airway obstruction are more likely to quit smoking [J].

Bednarek, M. ;

Gorecka, D. ;

Wielgomas, J. ;

Czajkowska-Malinowska, M. ;

Regula, J. ;

Mieszko-Filipczyk, G. ;

Jasionowicz, M. ;

Bijata-Bronisz, R. ;

Lempicka-Jastrzebska, M. ;

Czajkowski, M. ;

Przybylski, G. ;

Zielinski, J. .

THORAX, 2006, 61 (10) :869-873

[9]

Electronic Cigarettes: A Short Review [J].

Bertholon, J. F. ;

Becquemin, M. H. ;

Annesi-Maesano, I. ;

Dautzenberg, B. .

RESPIRATION, 2013, 86 (05) :433-438

[10]

Comparison of spirometric thresholds in diagnosing smoking-related airflow obstruction [J].

Bhatt, Surya P. ;

Sieren, Jessica C. ;

Dransfield, Mark T. ;

Washko, George R. ;

Newell, John D., Jr. ;

Stinson, Douglas S. ;

Zamba, Gideon K. D. ;

Hoffman, Eric A. .

THORAX, 2014, 69 (05) :409-414

← 1 2 3 4 5 6 7 8 9 10 →