INHIBITORS OF PROTEIN-TYROSINE KINASES

被引：33

作者：

FRY, DW ^{[1
]}

BRIDGES, AJ ^{[1
]}

机构：

[1] WARNER LAMBERT PARKE DAVIS, PARKE DAVIS PHARMACEUT RES, DEPT CHEM, ANN ARBOR, MI 48105 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1995年 / 6卷 / 06期

关键词：

D O I：

10.1016/0958-1669(95)80109-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The description in the past year of several novel protein tyrosine kinase inhibitors, which exhibit dramatic improvements in potency and specificity over earlier agents, will be considered a major turning point in the field. These compounds appear to have the necessary pharmacological properties to finally allow clarification of whether suppression of specific tyrosine kinases is of therapeutic benefit in certain disease states.

引用

页码：662 / 667

页数：6

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