TETRAZOLIUM SALTS - ANTAGONISM OF ACETYLCHOLINE AND HISTAMINE RESPONSE ON ISOLATED GUINEAPIG ILIUM BY 2-3-5-TRIPHENYL-TETRAZOLIUM CHLORIDE

被引：1

作者：

CHAUHAN, PS

BASURAY, B

机构：

[1] Indian Institute of Experimental Medicine, Jadavpur, Calcutta-32 and St. John's Medical College, Bangalore

来源：

LIFE SCIENCES PART 1 PHYSIOLOGY AND PHARMACOLOGY AND PART 2 BIOCHEMISTRY GENERAL AND MOLECULAR BIOLOGY | 1969年 / 8卷 / 13P1期

关键词：

D O I：

10.1016/0024-3205(69)90262-8

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Effect of 2:3:5 Triphenyl-tetrazolium chloride (TTC), a known electron acceptor, which has been reported to uncouple oxidative phosphorylation was studied on acetycholine and histamine-induced contraction of the isolated guineapig ilium. TTC was found to antagonize responses of acetylcholine and histamine on this tissue. Although, higher doses of TTC produced a noncompetitive blockade of the agonists, there was, however, a definitive shift of the dose response curves to the right at relatively lower doses of TTC. © 1969.

引用

页码：733 / &

共 9 条

[1]

ALLEN EG, 1966, J BACT, V92, P104

[2]

ARIENS EJ, 1960, ARCH INT PHARMACOD T, V127, P459

[3] TETRAZOLIUM SALT - ANTAGONISM OF ACETYLCHOLINE-INDUCED RESPONSE ON FROGS RECTUS [J].