STEREOCONVERGENT SYNTHESIS OF A POTENT MOSQUITO LARVICIDE - (2E,4E,8E,10Z)-N-(2-METHYL PROPYL)-2,4,8,10-DODECATETRAENEAMIDE

被引：8

作者：

SHARMA, GVM

SHEKHARAM, T

UPENDER, V

机构：

[1] Indian Institute of Chemical Technology, Hyderabad

来源：

TETRAHEDRON | 1990年 / 46卷 / 16期

关键词：

D O I：

10.1016/S0040-4020(01)87765-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

First total synthesis of (2E,4E,8E,10Z)-N-(2-methyl propyl)-2,4,8,10-dodecatetraene amide (1), by the condensation of (4E,6Z)-octadienyl phenyl sulfone (2) and ethyl-4-oxobutanoate (3) followed by double elimination reaction, which involves easily accessible reagents and simple transformations is described. © 1990.

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页码：5665 / 5672

页数：8

相关论文

共 17 条

[1] POLYACETYLENIC COMPOUNDS .256. NEW AMIDES FROM SPILANTHES-ALBA [J].

BOHLMANN, F ;

ZIESCHE, J ;

ROBINSON, H ;

KING, RM .

PHYTOCHEMISTRY, 1980, 19 (07) :1535-1537

[2] SYNTHESIS OF BIOLOGICALLY-ACTIVE UNSATURATED AMIDES [J].

BOHLMANN, F ;

GANZER, M ;

KRUGER, M ;

NORDHOFF, E .

TETRAHEDRON, 1983, 39 (01) :123-128

[3]

BRANDSMA L, 1961, PREPARATIVE ACETYLEN, P64

[4] POLYACETYLENIC COMPOUNDS .260. AMIDES FROM ACHILLEA SPECIES AND LEUCCYCLUS-FORMOSUS [J].

GREGER, H ;

GRENZ, M ;

BOHLMANN, F .

PHYTOCHEMISTRY, 1981, 20 (11) :2579-2581

[5] NEW AMIDE FROM PIPER-OFFICINARUM [J].

GUPTA, OP ;

GUPTA, SC ;

DHAR, KL ;

ATAL, CK .

PHYTOCHEMISTRY, 1977, 16 (09) :1436-1437

[6]

HASSANALI A, 1989, ACS SYM SER, P78

[7] RESEARCHES ON ACETYLENIC COMPOUNDS .13. THE REACTION BETWEEN EPICHLOROHYDRIN AND SODIUM ACETYLIDE - A NOVEL ROUTE TO THE ETHYNYL-ETHYLENIC ALCOHOL, PENT-2-EN-4-YN-1-OL [J].

HAYNES, LJ ;

HEILBRON, I ;

JONES, ERH ;

SONDHEIMER, F .

JOURNAL OF THE CHEMICAL SOCIETY, 1947, (NOV) :1583-1585

[8]

JACOBSON M, 1975, USDA AGR HDB, P461

[9] A MOSQUITO LARVICIDE IN SPILANTHES-MAURITIANA [J].

JONDIKO, IJO .

PHYTOCHEMISTRY, 1986, 25 (10) :2289-2290

[10]

KOTWARO JO, 1976, MED PLANTS E AFRICA, P71