SUSCEPTIBILITY OF VARIOUS CELLS TREATED WITH INTERFERON TO THE TOXIC EFFECT OF POLY(RI).POLY(RC) TREATMENT

被引：14

作者：

EMENY, JM ^{[1
]}

MORGAN, MJ ^{[1
]}

机构：

[1] UNIV LEICESTER,DEPT BIOCHEM,LEICESTER LE1 7RH,ENGLAND

来源：

JOURNAL OF GENERAL VIROLOGY | 1979年 / 43卷 / APR期

关键词：

D O I：

10.1099/0022-1317-43-1-253

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Various cells were treated with interferon and then exposed to polyriboinosinic-polyribocytidylic acid complex [poly(rI).poly(rC)]. With mouse L cells, there was a marked cytotoxic effect from low doses of interferon and poly(rI).poly(rC), whereas chick embryo cells showed an effect only after high doses. When primate cells (LLC.Mk2, BSC.B, Vero and human embryo cells) were treated with human or monkey interferon, poly(rI).poly(rC) was not cytotoxic.

引用

页码：253 / 255

页数：3

共 8 条

[1]

EMENY JM, 1979, J GENERAL VIROLOGY

[2] DYE UPTAKE METHODS FOR ASSESSING VIRAL CYTOPATHOGENICITY AND THEIR APPLICATION TO INTERFERON ASSAYS [J].