SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 5-(4-CHLOROBENZOYL)-4-(HYDROXYMETHYL)-1-METHYL-1H-PYRROLE-2-ACETIC ACID, A MAJOR METABOLITE OF ZOMEPIRAC SODIUM

被引：11

作者：

ANDERSON, NG ^{[1
]}

CARSON, JR ^{[1
]}

机构：

[1] MCNEIL LABS INC,DEPT CHEM RES,FT WASHINGTON,PA 19034

来源：

关键词：

D O I：

10.1021/jm00175a022

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：98 / 100

页数：3

共 18 条

[1] SOME BIOLOGICAL PROPERTIES OF 2-(4-ISOBUTYLPHENYL)-PROPIONIC ACID
ADAMS, SS
CLIFFE, EE
LESSEL, B
NICHOLSON, JS
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1967, 56 (12) : 1686 - +
[2] ADAMS SS, 1969, ARCH INT PHARMACOD T, V178, P115
[3] AGGREGATION OF BLOOD PLATELETS BY ADENOSINE DIPHOSPHATE AND ITS REVERSAL
BORN, GVR
[J]. NATURE, 1962, 194 (4832) : 927 - &
[4] CAMPS F, 1978, SYNTHESIS-STUTTGART, P215
[5] CARMOSIN RJ, 1978, Patent No. 4125537
[6] 5-BENZOYL-1-METHYLPYRROLE-2-ACETIC ACIDS AS ANTIINFLAMMATORY AGENTS .2. 4-METHYL COMPOUNDS
CARSON, JR
WONG, S
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1973, 16 (02) : 172 - 174
[7] COOPER S, 1977, J DENT RES A, V56, P140
[8] COOPER SA, 1977, CLIN PHARMACOL THER, V21, P101
[9] GOSSAUER A, 1974, CHEM PYRROLE, P120
[10] GRINDEL JM, 1978, FED PROC, V37, P691