TRANSCRIPTION FACTOR BASED THERAPEUTICS - DRUGS OF THE FUTURE

被引：22

作者：

PETERSON, MG

BAICHWAL, VR

机构：

[1] Tularik, Inc., South San Francisco, CA 94080

来源：

TRENDS IN BIOTECHNOLOGY | 1993年 / 11卷 / 01期

关键词：

D O I：

10.1016/0167-7799(93)90069-L

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

During the past decade there has been an explosion of information relating to our understanding of eukaryotic gene expression. The identification of transcription factors as the key regulatory molecules in this process, and the analysis of their structure and function have revealed that these proteins are potential targets for therapeutic intervention.

引用

页码：11 / 17

页数：7

共 30 条

[1]

BROWN MS, 1990, PHARM BASIS THERAPEU

[2]

DALLAFAVERA R, 1991, ORIGINS HUMAN CANCER

[3] ISOLATION OF TRANSCRIPTION FACTORS THAT DISCRIMINATE BETWEEN DIFFERENT PROMOTERS RECOGNIZED BY RNA POLYMERASE-II [J].