DIRECTIVE SEGREGATION IS THE BASIS OF COLE1 PLASMID INCOMPATIBILITY

被引:22
作者
BEDBROOK, JR [1 ]
LEHRACH, H [1 ]
AUSUBEL, FM [1 ]
机构
[1] HARVARD UNIV,DEPT BIOL,BIOL LAB,CAMBRIDGE,MA 02138
关键词
D O I
10.1038/281447a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Incompatibility between ColE1 plasmids in Escherichia coli can be explained by competition for a limited number of replication sites. These sites ensure directive segregation of plasmids to daughter cells on cell division. The number of sites can be more than one only if a linear segregation mechanism is postulated. © 1979 Nature Publishing Group.
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页码:447 / 452
页数:6
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