EFFECTS OF TAXOL ON THE MACROPHAGE FUNCTION - INTERACTIONS WITH SOME IMMUNOLOGICAL PARAMETERS

被引：11

作者：

BOTTEXGAUTHIER, C ^{[1
]}

CONDEMINE, F ^{[1
]}

PICOT, F ^{[1
]}

VIDAL, D ^{[1
]}

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91190 GIF SUR YVETTE,FRANCE

来源：

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY | 1992年 / 14卷 / 1-2期

关键词：

D O I：

10.3109/08923979209009212

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The effects of Taxol on some immunological parameters were investigated, in vitro, in the murine macrophage cell line J774.1. Mitochondrial dehydrogenase activity and (H-3) TdR incorporation were shown to be increased in Taxol treated cells. Likewise, Taxol induced TNF alpha secretion. But Taxol seemed to be a weak inducer of the two interleukins IL-1 and IL-2, since their detection occured late in the cell culture supernatants.

引用

页码：39 / 61

页数：23

共 19 条

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