IS THE RECOMMENDED DAILY ALLOWANCE FOR VITAMIN-D TOO LOW FOR THE HOMEBOUND ELDERLY

被引:69
作者
GLOTH, FM
TOBIN, JD
SHERMAN, SS
HOLLIS, BW
机构
[1] JOHNS HOPKINS UNIV,SCH MED,DEPT MED,DIV GERIATR MED & GERONTOL,BALTIMORE,MD 21205
[2] FRANCIS SCOTT KEY MED CTR,BALTIMORE,MD
[3] MED UNIV S CAROLINA,CHILDRENS HOSP,DEPT PEDIAT,CHARLESTON,SC 29425
关键词
D O I
10.1111/j.1532-5415.1991.tb01615.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
A population of sunlight-deprived elderly was studied to determine the daily intake of vitamin D and whether dietary intake was sufficient to maintain a normal vitamin D status. Twenty-two subjects over 65 years old with serum creatinine < 180 mu-mol/L and confined indoors for more than 6 months were chosen from the community and a nursing home in Southeast Baltimore. Three-day food records were obtained along with serum levels of 25-hydroxyvitamin D (25-OHD), 1,25-dihydroxyvitamin D (1,25-(OH)2 D), and intact parathyroid hormone (PTH). The mean daily vitamin D intake was over twofold greater than the adult Recommended Daily Allowance (RDA) of 200 IU. The mean 25-OHD level was 40 nmol/L (normal 25-138 nmol/L) with seven patients less than 25 nmol/L. Of those participants with 25-OHD values less than 25 nmol/L, the mean vitamin D intake was 467 IU (range 36-1096 IU). We conclude that the current RDA seems inadequate for many older individuals who do not get sun exposure. This particular population of elderly is at risk to develop vitamin D deficiency and the associated complications.
引用
收藏
页码:137 / 141
页数:5
相关论文
共 34 条
  • [1] SERUM LEVELS OF VITAMIN-D METABOLITES IN THE ELDERLY
    AKSNES, L
    RODLAND, O
    ODEGAARD, OR
    BAKKE, KJ
    AARSKOG, D
    [J]. ACTA ENDOCRINOLOGICA, 1989, 121 (01): : 27 - 33
  • [3] BAKER MR, 1980, AGE AGEING, V9, P249, DOI 10.1093/ageing/9.4.249
  • [4] BARAGRY JM, 1978, CLIN SCI MOL MED, V55, P213
  • [5] BARZEL US, 1986, MAYO CLIN PROC, V61, P303, DOI 10.1016/S0025-6196(12)61936-3
  • [6] VITAMIN-D STATUS IN THE ELDERLY - SEASONAL SUBSTRATE DEFICIENCY CAUSES 1,25-DIHYDROXYCHOLECALCIFEROL DEFICIENCY
    BOUILLON, RA
    AUWERX, JH
    LISSENS, WD
    PELEMANS, WK
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1987, 45 (04) : 755 - 763
  • [7] SERUM VITAMIN-D2 AND VITAMIN-D3 METABOLITE CONCENTRATIONS AND ABSORPTION OF VITAMIN-D2 IN ELDERLY SUBJECTS
    CLEMENS, TL
    ZHOU, XY
    MYLES, M
    ENDRES, D
    LINDSAY, R
    [J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1986, 63 (03) : 656 - 660
  • [8] CORLESS D, 1975, LANCET, V1, P1404
  • [9] CORLESS D, 1979, GERONTOLOGY, V24, P350
  • [10] EXTONSMITH AN, 1966, LANCET, V2, P999