HIPPOCAMPAL PYRAMIDAL CELL LOSS IN HUMAN STATUS EPILEPTICUS

被引：159

作者：

DEGIORGIO, CM

TOMIYASU, U

GOTT, PS

TREIMAN, DM

机构：

[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT NEUROL,LOS ANGELES,CA 90024

[2] UNIV SO CALIF,SCH MED,DEPT NEUROL,EEG EVOKED POTENTIAL LAB,LOS ANGELES,CA 90033

[3] UNIV CALIF LOS ANGELES,SCH MED,DEPT PATHOL,LOS ANGELES,CA 90024

[4] VET ADM MED CTR,LAB SERV,LOS ANGELES,CA

[5] VET ADM MED CTR BRENTWOOD,NEUROL SERV,LOS ANGELES,CA 90073

[6] VET ADM MED CTR BRENTWOOD,RES SERV,LOS ANGELES,CA 90073

来源：

EPILEPSIA | 1992年 / 33卷 / 01期

关键词：

HIPPOCAMPUS; STATUS EPILEPTICUS; PYRAMIDAL CELLS;

D O I：

10.1111/j.1528-1157.1992.tb02278.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A pilot case-control quantitative study of the hippocampus in patients with severe status epilepticus was performed to identify specific patterns of pyramidal cell loss. Pyramidal cell densities from five patients who died following status epilepticus were compared with five normal controls and five controls matched for age, hypoxia/ischemia, previous epilepsy, and alcohol abuse. Neuronal densities were greatest in the normal control group and least in patients with status epilepticus. Significant reductions were identified in Sommer's sector (prosubiculum and CA1) as well as in CA3 when compared to normal controls.

引用

页码：23 / 27

页数：5

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