SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 28-HOMOBRASSINOLIDE AND ANALOGS

被引：35

作者：

MCMORRIS, TC

PATIL, PA

CHAVEZ, RG

BAKER, ME

CLOUSE, SD

机构：

[1] UNIV CALIF SAN DIEGO,DEPT MED,LA JOLLA,CA 92093

[2] SAN DIEGO STATE UNIV,DEPT BIOL,SAN DIEGO,CA 92182

来源：

PHYTOCHEMISTRY | 1994年 / 36卷 / 03期

关键词：

BRASSINOSTEROIDS; 28-HOMOBRASSINOLIDE; STIGMASTEROL; SOYBEAN EPICOTYL ELONGATION; SIDE CHAIN CONFORMATION;

D O I：

10.1016/S0031-9422(00)89779-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

28-Homobrassinolide has been synthesized from stigmasterol in an overall yield of 21%. The biological activity of 28-homobrassinolide, brassinolide, 24-epiibrassinoide, 22S,23S,24-epibrassinolide, and 22S,23S,28-homobrassinolides have been compared in the soybean epicotyl elongation assay. All the steroids except 22S,23S,28-homobrassinolide exhibited a similar biological activity, but the latter compound was substantially less active. There appears to be a correlation between biological activity and overall dimensions of the steroidal side chain.

引用

页码：585 / 589

页数：5

共 17 条

[1] OCCURRENCE OF 3 NEW BRASSINOSTEROIDS - BRASSINONE, (24S)-24-ETHYLBRASSINONE AND 28-NORBRASSINOLIDE, IN HIGHER-PLANTS [J].