DISTRIBUTION OF CHOLINERGIC NEURON-SPECIFIC GANGLIOSIDES (GT1A-ALPHA AND GQ1B-ALPHA) IN THE RAT CENTRAL-NERVOUS-SYSTEM

被引：15

作者：

IRIE, F

HASHIKAWA, T

TAI, T

SEYAMA, Y

HIRABAYASHI, Y

机构：

[1] RIKEN,INST PHYS & CHEM RES,FRONTIER RES PROGRAM,GLYCO CELL BIOL LAB,WAKO,SAITAMA 35101,JAPAN

[2] RIKEN,INST PHYS & CHEM RES,FRONTIER RES PROGRAM,NEURAL SYST LAB,WAKO,SAITAMA 35101,JAPAN

[3] UNIV TOKYO,FAC MED,DEPT PHYSIOL CHEM & NUTR,BUNKYO KU,TOKYO 113,JAPAN

[4] TOKYO METROPOLITAN INST MED SCI,DEPT TUMOR IMMUNOL,TOKYO 113,JAPAN

来源：

BRAIN RESEARCH | 1994年 / 665卷 / 01期

基金：

日本学术振兴会;

关键词：

GANGLIOSIDE; CHOLINERGIC NEURON; IMMUNOHISTOCHEMISTRY; RAT CENTRAL NERVOUS SYSTEM;

D O I：

10.1016/0006-8993(94)91169-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A newly developed mouse monoclonal antibody, GGR-41, was used to localize a novel species of gangliosides, GT1a alpha and GQ1b alpha, in the rat central nervous system. Intense immunoreactivity was found in the neuropil of the spinal cord dorsal horn, spinal trigeminal nucleus, solitary tract nucleus, superior colliculus, interpeduncular nucleus, hypothalamus and septal area. The results suggest that GT1a alpha and GQ1b alpha are expressed in the nerve terminals of a certain population of cholinergic fibers.

引用

页码：161 / 166

页数：6

共 26 条

[1] CHOLINERGIC AND NON-CHOLINERGIC FOREBRAIN PROJECTIONS TO THE INTERPEDUNCULAR NUCLEUS [J].