NUCLEOTIDE-SEQUENCE OF THE CDNA-ENCODING HUMAN HELIX-LOOP-HELIX ID-1 PROTEIN - IDENTIFICATION OF FUNCTIONALLY CONSERVED RESIDUES COMMON TO ID PROTEINS

被引：28

作者：

DEED, RW ^{[1
]}

JASIOK, M ^{[1
]}

NORTON, JD ^{[1
]}

机构：

[1] CHRISTIE HOSP NATL HLTH SERV TRUST,PATERSON INST CANC RES,CRC,DEPT GENE REGULAT,MANCHESTER M20 9BX,ENGLAND

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1994年 / 1219卷 / 01期

基金：

英国医学研究理事会;

关键词：

CDNA SEQUENCE; HELIX-LOOP-HELIX; TRANSCRIPTION FACTOR;

D O I：

10.1016/0167-4781(94)90261-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have determined the cDNA sequence encoding a 154 amino acid human Id-1 helix-loop-helix protein. Comparison with the amino acid sequences of human and mouse Id-2 and Id-3 proteins, reveals conservation/divergence of several residues in the helix-loop-helix domain known to be important for heterodimerisation, together with a common casein kinase II phosphorylation site.

引用

页码：160 / 162

页数：3

共 14 条

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