4-SUBSTITUTED NICOTINIC ACIDS AND NICOTINAMIDES .2. PREPARATION OF 4-METHYLNICOTINAMIDE RIBOSIDE

被引:20
作者
JARMAN, M
ROSS, WCJ
机构
[1] Chester Beatty Research Institute
来源
JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 02期
关键词
D O I
10.1039/j39690000199
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An improved method for the synthesis of nicotinamide ribosides is described. Nicotinamide and 4-methylnicotinamide condense with 3,5-di-O-benzoyl-D-ribofuranosyl chloride to give the dibenzoylribofuranosides in good yield. The ribosides obtained by mild hydrolysis contain predominantly the β-anomer.
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页码:199 / &
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