PRESYNAPTIC EXCITABILITY CHANGES INDUCED BY MORPHINE IN SINGLE CUTANEOUS AFFERENT C-FIBERS AND A-FIBERS

被引：83

作者：

CARSTENS, E ^{[1
]}

TULLOCH, I ^{[1
]}

ZIEGLGANSBERGER, W ^{[1
]}

ZIMMERMANN, M ^{[1
]}

机构：

[1] MAX PLANCK INST PSYCHIAT,D-8000 MUNICH 40,FED REP GER

来源：

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY | 1979年 / 379卷 / 02期

关键词：

C-fiber terminals; Excitability testing; Morphine; Presynaptic inhibition;

D O I：

10.1007/BF00586940

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Intraspinal microstimulation was used to test the excitability of single cutaneous (sural) A- and C-fibers at their central terminals in the cat. Systemic morphine (1.0-2.6 mg/kg) increased the antidromic threshold to 110% (mean value) of control in C-fibers. In some of the C-fibers this effect was reversed by naloxone. A-fibers were not consistently affected by mophine. © 1979 Springer-Verlag.

引用

页码：143 / 147

页数：5

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