THE ASSOCIATION OF HLA-B5 ANTIGEN WITH SPECIFIC MANIFESTATIONS OF BEHCETS-DISEASE

被引：31

作者：

AZIZLERLI, G ^{[1
]}

AKSUNGUR, VL ^{[1
]}

SARICA, R ^{[1
]}

AKYOL, E ^{[1
]}

OVUL, C ^{[1
]}

机构：

[1] CUKUROVA MED FAC,DEPT DERMATOL,ADANA,TURKEY

来源：

DERMATOLOGY | 1994年 / 188卷 / 04期

关键词：

BEHCETS DISEASE; HLA-B5; ANTIGEN;

D O I：

10.1159/000247169

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 [皮肤病与性病学];

摘要：

The HLA-BS phenotype was investigated in 235 patients with Behcet's disease and in 100 healthy persons. HLA-BS was more frequent in the patients (77 vs. 30% p<0.001, relative risk=7.8). The frequency of HLA-BS was higher in patients with genital ulceration than without (82.3 vs. 63%, p<0.01). Patients with thrombophlebitis showed a less frequent positivity of HLA-BS antigen than the patients without thrombophlebitis (50 vs. 79.2%, p<0.02). These results suggest that HLA-BS-related genes not only affect the development of Behcet's disease but also the occurrence of its clinical manifestations.

引用

页码：293 / 295

页数：3