NON-MUTAGENICITY FOR SALMONELLA OF THE CHLORINATED HYDROCARBONS AROCLOR 1254, 1,2,4-TRICHLOROBENZENE, MIREX AND KEPONE

被引：35

作者：

SCHOENY, RS ^{[1
]}

SMITH, CC ^{[1
]}

LOPER, JC ^{[1
]}

机构：

[1] UNIV CINCINNATI,COLL MED,DEPT MICROBIOL,KETTERING LAB,CINCINNATI,OH 45267

来源：

MUTATION RESEARCH | 1979年 / 68卷 / 02期

关键词：

D O I：

10.1016/0165-1218(79)90140-X

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A polychlorinated biphenyl mixture, Aroclor 1254, two commercial grade insecticides, mirex and kepone, and a pesticide breakdown product, 1,2,4-trichlorobenzene were evaluated for mutagenicity and hepatic enzyme induction potential in the Salmonella/microsomal assay. None was found to revert strains TA1535, TA1537, TA98 or TA100 when tested with or without metabolic activation. Liver microsomal extracts (S9) from rats induced with 1,2,4-trichlorobenzene were shown to differ from S9 of either control or Aroclor 1254-induced rats in the capacity to activate 2-aminoanthracene mutagenesis. © 1979.

引用

页码：125 / 132

页数：8

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