INSITU LOCALIZATION OF NF-H NEUROFILAMENT SUBUNIT MESSENGER-RNAS IN RAT-BRAIN

被引：13

作者：

ROUSSEL, G

FELIX, JM

DAUTIGNY, A

PHAMDINH, D

HINDELANG, C

JOLLES, P

NUSSBAUM, JL

机构：

[1] INSERM,U44,F-67200 STRASBOURG,FRANCE

[2] UNIV STRASBOURG 1,PHYSIOL GEN LAB,CNRS,UA 309,F-67070 STRASBOURG,FRANCE

[3] UNIV PARIS 05,PROT LAB,CNRS,USA 1188,F-75270 PARIS 06,FRANCE

来源：

DEVELOPMENTAL NEUROSCIENCE | 1991年 / 13卷 / 02期

关键词：

NF-H NEUROFILAMENT SUBUNIT; INSITU HYBRIDIZATION; RAT BRAIN ONTOGENY;

D O I：

10.1159/000112146

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The expression of NF-H neurofilament subunit mRNAs was investigated in the rat brain at different ontogenic stages. The levels of NF-H mRNAs vary 15-fold among brain regions with the highest level in the brainstem. In situ localization studies revealed that the NF-H mRNAs are mainly concentrated in the brainstem motoneuron nuclei. By increasing the sensitivity of the hybridization method, NF-H mRNAs could also be localized in neurons present in the cortex, thalamus and hippocampus areas. Minor amounts of NF-H mRNAs were already detected at 17-day embryonic stages.

引用

页码：98 / 103

页数：6

共 32 条

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