2 CASES OF LONG-TERM DOPAMINE D2 RECEPTOR BLOCKADE AFTER DEPOT NEUROLEPTICS

被引：12

作者：

HARASKOVANDERMEER, C ^{[1
]}

BRUCKE, T ^{[1
]}

WENGER, S ^{[1
]}

FISCHER, P ^{[1
]}

DEECKE, L ^{[1
]}

PODREKA, I ^{[1
]}

机构：

[1] UNIV VIENNA,PSYCHIAT CLIN,A-1090 VIENNA,AUSTRIA

来源：

JOURNAL OF NEURAL TRANSMISSION-GENERAL SECTION | 1993年 / 94卷 / 03期

关键词：

DOPAMINE D2 RECEPTORS; DEPOT NEUROLEPTICS; EXTRAPYRAMIDAL SIDE EFFECTS; IBZM-SPECT;

D O I：

10.1007/BF01277026

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Two patients with extrapyramidal side effects after the use of fluphenazine decanoate were evaluated by means of IBZM-SPECT. Dopamine D2 receptor occupancy 1.5 months after withdrawal still amounted to 83% and 50%. More attention should be focused on long term effects of neuroleptics.

引用

页码：217 / 221

页数：5

共 8 条

[1] STRIATAL DOPAMINE RECEPTOR OCCUPANCY DURING AND FOLLOWING WITHDRAWAL FROM NEUROLEPTIC TREATMENT - CORRELATIVE EVALUATION BY POSITRON EMISSION TOMOGRAPHY AND PLASMA PROLACTIN LEVELS [J].