DYNAMIC ANALYSIS OF VENTRICULAR REPOLARIZATION DURATION FROM 24-HOUR HOLTER RECORDINGS

被引:64
作者
MERRI, M
ALBERTI, M
MOSS, AJ
机构
[1] UNIV ROCHESTER,DEPT PREVENT & COMMUNITY MED,HEART RES FOLLOWUP PROGRAM,ROCHESTER,NY 14627
[2] UNIV ROCHESTER,DEPT ELECT ENGN,ROCHESTER,NY 14627
关键词
D O I
10.1109/10.250577
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Evaluation of the influence of the autonomic nervous system on the ventricular repolarization duration was carried out using beat-to-beat analysis of the time intervals between the peaks of the R and T waves (RTm). After pre-processing of digitized Holter ECG's, auto and cross spectrum analyses were applied to heart rate and repolarization duration variability signals. Coherence analysis was used to assess the existence of common spectral contributions. The heart rate variability signal was used as reference of the sympatho-vagal balance at the sinus node. It was found that, in normal individuals, the autonomic nervous system directly influences the ventricular repolarization duration and that this influence is qualitatively very similar to the one that modulates the heart rate. Pathological alteration of these parallel autonomic activities to the heart (on the sinus node and on the ventricle) might cause uncoupling between depolarization and repolarization.
引用
收藏
页码:1219 / 1225
页数:7
相关论文
共 24 条
[1]  
Akselrod S., Et al., Power spectrum analysis of heart rate fluctuations: A quantitative probe of beat-to-beat cardiovascular control, Science, 213, pp. 220-222, (1981)
[2]  
Baselli G., Et al., Heart rate variability signal processing: A quantitative approach as as aid to diagnosis in cardiovascular pathologies, Int. J. Bio-Med. Comp., 20, pp. 51-70, (1987)
[3]  
Sayers B.M.A., Analysis of heart rate variability, Ergonomics, 16, pp. 17-32, (1973)
[4]  
Pomeranz B., Et al., Assessment of autonomic function in humans by heart rate spectral analysis, Amer. J. Physiol, pp. H151-H153, (1985)
[5]  
Pagani M., Et al., Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog, Circulation Res., 59, pp. 178-193, (1986)
[6]  
Cerutti S., Et al., Automatic assessment of the interaction between respiration and heart rate variability signal, Medic, Progr. Through Technol., 14, 1, pp. 7-19, (1988)
[7]  
Kitney R.I., Rompelman O., The Study of Heart Rate Variability, (1980)
[8]  
Moss A.J., Schwartz P.J., Delayed repolarization (QT or QTU prolongation) and malignant ventricular arthythmias, Mod. Concepts Cardiovac Dis., 51, pp. 85-90, (1982)
[9]  
Mem M., Benhorin J., Alberti M., Locati E., Moss A.J., Electrocardiographic quantitation of ventricular repolarization, Circulation, 80, pp. 1301-1308, (1989)
[10]  
Mem M., Alberti M., Benhorin J., Moss A.J., Preprocessing of holter ECGs for analysis of the dynamic interrelations between heart rate and repolarization duration variabilities, J. Electrocardiography, 235, pp. 157-162, (1991)