CYTOGENETIC STUDIES IN 5 PATIENTS WITH SEZARY-SYNDROME

被引：13

作者：

SOLE, F

WOESSNER, S

VALLESPI, T

LOSADA, AP

FLORENSA, L

IRRIGUIBLE, D

VILA, J

SANSSABRAFEN, J

机构：

[1] UNIV BARCELONA,HOSP GEN VALLE HEBRON,SERV HEMATOL & HEMOTERAPIA,BARCELONA,SPAIN

[2] HOSP SAGRAT COR,UNITAT HEMATOL,BARCELONA,SPAIN

来源：

CANCER GENETICS AND CYTOGENETICS | 1994年 / 75卷 / 02期

关键词：

D O I：

10.1016/0165-4608(94)90164-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A cytogenetic study was performed in five patients with Sezary syndrome. Metaphases were obtained from a phytohemaggluyinin-stimulated lymphocyte culture. The five patients showed abnormal karyotypes. The chromosomes preferentially involved in numerical aberrations were chromosomes 10 (monosomy) and 13 (monosomy); involved in structural changes were chromosomes 1, 2, 4, 6, and 14. In our series, all patients showed progression of the disease.

引用

页码：130 / 132

页数：3

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