MRI ALTERATIONS AS AN EARLY FINDING IN CREUTZFELD-JAKOB DISEASE

被引:24
作者
TARTARO, A [1 ]
FULGENTE, T [1 ]
PIZZI, CD [1 ]
BONOMO, L [1 ]
BOCOLA, V [1 ]
ONOFRJ, M [1 ]
机构
[1] UNIV G DANNUNZIO,INST NEUROL SCI,CHIETI,ITALY
关键词
BRAIN; CREUTZFELDT-JAKOB DISEASE; MRI; CT; MAGNETIC RESONANCE (MR); COMPUTED TOMOGRAPHY;
D O I
10.1016/0720-048X(93)90095-5
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Two cases of Creutzfeldt-Jakob Disease (CJD) are reported. In both cases, pathologically confirmed, magnetic resonance imaging (MRI) showed bilateral altered signal areas in the basal ganglia, early in the course of the disease. The CT scan, although performed later than MRI, confirmed these findings. Only in one patient did electroencephalography (EEG) show typical triphasic sharp-waves, but this support to clinical diagnosis was obtained 1 month after the appearance of MRI alterations.
引用
收藏
页码:155 / 158
页数:4
相关论文
共 18 条
[1]  
Masters, Richardson, Subacute spongiform encephalopathy (Creutzfeldt-Jakob disease) — the nature and progression of spongiform change, Brain, 101, pp. 333-344, (1978)
[2]  
Davanipour, Alter, Sobel, Creutzfeldt-Jakob disease, Neurol Clin, 4, pp. 415-426, (1988)
[3]  
Brown, Chatala, Gajdusek, Gajdusek, Creutzfeldt-Jakob disease: clinical analysis of a consecutive series of 230 neuropathologically verified cases, Ann Neurol, 20, pp. 597-602, (1986)
[4]  
Gibbs, Gajdusaek, Ascher, Creutzfeldt-Jakob disease (subacute spongiform encephalopathy): transmission to the chimpanzee, Science, 161, pp. 388-389, (1968)
[5]  
Manuelidis, Kim, Angelo, Manuelidis, Serial propagation of Creutzfeldt-Jakob disease in guinea pigs, Proc Natl Acad Sci USA, 73, pp. 223-227, (1976)
[6]  
Manuelidis, Angelo, Gorgacz, Manuelidis, Transmission of Creutzfeldt-Jakob disease to Syrian hamster, Lancet, 1, (1977)
[7]  
Tateishi, Doi, Sato, Suetsugu, Ishii, Kuroiwa, Experimental transmission of human subacute spongiform encephalopathy to small rodents. III. Further transmission from three patients and distribution patterns of lesions in mice, Acta Neurophatol Berl, 53, pp. 161-163, (1981)
[8]  
Gaches, The electroencephalogram in genetic and transmissible dementia, Proceedings of the Xth International Congress of Neurology, 319, pp. 339-347, (1974)
[9]  
Chiofalo, Fuentes, Galvez, Serial EEG findings in 27 cases of Creutzfeldt-Jakob disease, Arch Neurol, 37, pp. 143-145, (1980)
[10]  
Lechi, Tedeschi, Mancia, Creutzfeldt-Jakob disease: Clinical EEG and neuropathological findings in a cluster of eleven patients, Ital Neurol Sci, 4, pp. 47-53, (1983)