ULTRASTRUCTURAL ASPECTS OF LYMPH-NODES IN INFANTILE PAPULAR ACRODERMATITIS . OBSERVATION OF VIRUS-LIKE PARTICLES

In infantile papular acrodermatitis, a mild generalized lymphadenopathy is common. The histologic picture resembles the one described as hyperplastic benign acute reticulitis. Electron microscopy showed hyperplasia and hypertrophy of littoral cells of lymphatic sinuses. These cells seem to derive from activated reticular cells. Furthermore, the authors noted virus-like particles in vacuoles and in lysosomes of littoral cells. This observation is discussed in relation to their nature and to the etiology of the disease. © 1968 S. Karger AG, Basel.