A COMPARATIVE STUDY OF HISTIDASE ACTIVITY IN AMPHIBIAN, AVIAN, REPTILIAN AND MAMMALIAN EPIDERMIS

被引：11

作者：

BADEN, HP

SVIOKLA, S

MADERSON, PF

机构：

[1] Department of Dermatology, the Harvard Medical School, Massachusetts General Hospital, Boston

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY | 1969年 / 30卷 / 05期

关键词：

epidermis; histidase; histidine; histidine deaminase; keratinization; keratohyalin; Skin; urocanic acid;

D O I：

10.1016/0010-406X(69)90043-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Histidase activity and urocanic acid have been demonstrated in the epidermis of most, but not all, eutherian mammals. 2. 2. The enzyme could not be detected in a variety of amphibian, avian and reptilian species. It was also absent in the one marsupial species tested. 3. 3. It is suggested that the presence of the histidine-to-urocanic acid pathway has significance as an evolutionary change and may be related to the formation of keratohyalin granules. © 1969.

引用

页码：889 / &

共 12 条

[1]

BADEN HP, 1968, CANCER RES, V28, P1463

[2]

BADEN HP, 1967, J NATL CANCER I, V38, P205

[3] METABOLISM AND FUNCTION OF UROCANIC ACID IN SKIN [J].