IMMUNIZATION WITH INACTIVATED POLIOVIRUS VACCINE AND ATTENUATED TYPE 3 POLIOVIRUS .I. VACCINATION WITH WM3 STRAIN IN 20 FAMILIES

In parenterally preimmunized families no spread of vaccine virus was observed from index children aged 5 to 8 years. After feeding of all family members the antibody response was found to be age dependent, i.e., the younger age groups reacted with higher antibody responses than the older ones. In members having only parenterally induced immunity, serum antibody levels below 48 BSU had no significant influence on time of excretion. © 1969 The C. V. Mosby Company.