SYNTHESIS OF CASEADINE METHYL ETHER

被引：50

作者：

CAVA, MP

LAKSHMIK.MV

MITCHELL, MJ

机构：

[1] Department of Chemistry, Wayne State University, Detroit

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1969年 / 34卷 / 09期

关键词：

D O I：

10.1021/jo01261a039

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Syntheses are described for the isomeric racemie bases 3,4,10,11-tetramethoxy-5,6,7,8,13,13a-hexahydrodibenzo[a,g]quinolizine (IX) and 1,2,10,11-tetramethoxy-5,6,7,8,13,13a-hexahydrodibenzo[a,g]quinolizine (X). The latter was shown to be the racemic form of the methyl ether of the novel tetrahydroprotoberberine base, (-)-caseadine, thus giving synthetic support to the caseadine structure la assigned by Chen, MacLean, and Manske on spectroscopic and biogenetic grounds. © 1969, American Chemical Society. All rights reserved.

引用

页码：2665 / +

页数：1

共 11 条

[1]

CHEN CY, 1968, TETRAHEDRON LETT, P349

[2]

DIE KONFIGURATION DES NATURLICHEN (+)-LAUDANOSINS SOWIE VERWANDTER TETRAHYDRO-ISOCHINOLIN, APORPHIN UND TETRAHYDRO-BERBERIN-ALKALOIDE [J].