COMPARISON OF RAPID TESTS FOR DETECTION OF GROUP-B STREPTOCOCCAL COLONIZATION

被引:9
作者
WALKER, CK [1 ]
CROMBLEHOLME, WR [1 ]
OHMSMITH, MJ [1 ]
SWEET, RL [1 ]
机构
[1] UNIV CALIF SAN FRANCISCO,SAN FRANCISCO GEN HOSP,DEPT OBSTET GYNECOL & REPROD SCI,ROOM 6D14,SAN FRANCISCO,CA 94110
关键词
D O I
10.1055/s-2007-999247
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Accurate rapid detection of maternal lower genital tract colonization with group B streptococci (GBS) in high-risk patients is essential for selective institution of intrapartum antibiotic treatment to reduce neonatal GBS infection. In this study, pure GBS isolates were used to evaluate five commercially available rapid tests in terms of speed, ease of use, and sensitivity. The products tested were Directigen, Equate, Bactigen, PathoDx, and Phadebact. Although each test could be performed relatively quickly, the ease of performance and level of sensitivity (10(5) to 10(8) CFU/ml) varied markedly. Quantitative cultures obtained from 17 known GBS carriers showed concentrations ranging from < 10(2) to >10(8) CFU/gm of vaginal material. Since only 40% of the women had greater-than-or-equal-to 10(5) CFU/gm of vaginal material, it appears that many colonized women would not be identified by these rapid tests.
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收藏
页码:304 / 308
页数:5
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