BENEFITS OF PLACENTAL BIOPSIES FOR RAPID KARYOTYPING IN THE 2ND AND 3RD TRIMESTERS (LATE CHORIONIC VILLUS SAMPLING) IN HIGH-RISK PREGNANCIES

被引：37

作者：

HOLZGREVE, W ^{[1
]}

MINY, P ^{[1
]}

GERLACH, B ^{[1
]}

WESTENDORP, A ^{[1
]}

AHLERT, D ^{[1
]}

HORST, J ^{[1
]}

机构：

[1] UNIV MUNSTER,INST HUMANGENET,W-4400 MUNSTER,GERMANY

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1990年 / 162卷 / 05期

关键词：

chromosomal anomalies; Placental biopsy; ultrasonographically abnormal pregnancy;

D O I：

10.1016/0002-9378(90)90014-X

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

In a total of 301 placental biopsies in the second and third trimesters, 225 were performed because of suspicious ultrasonographic findings. In this group there was a high rate of aneuploidies (20%). As opposed to the alternative methods for rapid karyotyping, placental biopsies can easily be performed even in pregnancies with abnormal amounts of amniotic fluid. Oligohydramnios and polyhydramnios were key ultrasonographic findings in 38% of cases and were found to be associated with 22% of abnormal chromosomal findings. Suggestive ultrasonographic findings seem to justify the exclusive use of direct preparation. © 1990.

引用

页码：1188 / 1192

页数：5

共 28 条

[1]

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[2]

ALVAREZ H, 1966, AM J OBSTET GYNECOL, V95, P538

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