REACTION OF FEB1M WITH DNA - FE(II)B1M-NO

被引：25

作者：

ANTHOLINE, WE ^{[1
]}

PETERING, DH ^{[1
]}

机构：

[1] UNIV WISCONSIN, DEPT CHEM, MOLEC BIOMED RES, MILWAUKEE, WI 53201 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 91卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0006-291X(79)91554-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structure of the iron bleomycin nitric oxide complex is altered in the presence of calf thymus DNA as determined from epr studies. This altered structure predominates for one iron bleomycin nitric oxide molecule per coil of the DNA helix. In the absence of nitric oxide, as the pH is lowered, iron bleomycin dissociates in two steps, supporting the hypothesis that in-plane nitrogens may be easily perturbed. © 1979.

引用

页码：528 / 533

页数：6

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