HYDROLYSIS OF A PHOSPHATE DIESTER DOUBLY COORDINATED TO A DINUCLEAR COBALT(III) COMPLEX - A NOVEL MECHANISM

被引：98

作者：

WAHNON, D ^{[1
]}

LEBUIS, AM ^{[1
]}

CHIN, J ^{[1
]}

机构：

[1] MCGILL UNIV, DEPT CHEM, MONTREAL, PQ H3A 2K6, CANADA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1995年 / 34卷 / 21期

关键词：

COBALT COMPOUNDS; ENZYME MODELS; HYDROLYZES; PHOSPHORUS COMPOUNDS;

D O I：

10.1002/anie.199524121

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nucleophilic attack of the bridging oxo ligand is the key step in the hydrolysis of the bridging phosphate diester in complex 1. This hydrolysis is 1012 times faster than the hydrolysis of the free phosphate diester. Thus, the phosphate‐free Co complex is an interesting model of enzymes having two metal atoms in the active site. (Figure Presented.) Copyright © 1995 by VCH Verlagsgesellschaft mbH, Germany

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页码：2412 / 2414

页数：3

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