PREPARATION AND EVALUATION OF A LONG-ACTING LIQUID ANTITUSSIVE PRODUCT

被引：8

作者：

PONGPAIBUL, Y

SAYED, H

WHITWORTH, CW

机构：

[1] UNIV GEORGIA,COLL PHARM,ATHENS,GA 30602

[2] CHIANG MAI UNIV,FAC PHARM,CHIANG MAI 5000,THAILAND

[3] UNIV ASSIUT,FAC PHARM,ASSIUT,EGYPT

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1990年 / 16卷 / 06期

关键词：

D O I：

10.3109/03639049009114919

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Microparticles containing a dextramothophan-resins complex were prepared by a modified emulsion solvent evaporation method. The particles were evaluated for size distribution and dissolution rate. Selected microparticles were suspended in various liquid media and stored at room tempertature. Dissolution of suspended in various liquid media and stored at room temperature. Dissolution of suspended microparticles was studied after storage up to 40 days. The particles were found to be stable and did not release drug in a supending media containing 30% propylene glycol, 35% syrup and 35% of 1% methylcellulose 1500 cps solution. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：935 / 943

页数：9

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