DISSEMINATED INTRAVASCULAR COAGULATION AFTER FACTOR-IX COMPLEX RESOLVED USING PURIFIED FACTOR-IX CONCENTRATE

被引：9

作者：

HADLEY, T ^{[1
]}

DJULBEGOVIC, B ^{[1
]}

机构：

[1] UNIV LOUISVILLE, JAMES GRAHAM BROWN CANC CTR, DEPT MED DIV MED ONCOL HEMATOL, LOUISVILLE, KY 40292 USA

来源：

ANNALS OF INTERNAL MEDICINE | 1991年 / 115卷 / 08期

关键词：

DISSEMINATED INTRAVASCULAR COAGULATION; FACTOR-IX; CHRISTMAS DISEASE; ANTIBODIES; MONOCLONAL; FACTOR-IX COMPLEX;

D O I：

10.7326/0003-4819-115-8-621

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A patient with hemophilia B developed disseminated intravascular coagulation during treatment with factor IX complex. Factor IX complex was withdrawn, and the patient was treated with monoclonal antibody-purified factor IX. The disseminated intravascular coagulation resolved during treatment with purified factor IX, indicating that purified factor IX does not sustain factor IX complex-induced disseminated intravascular coagulation. This is the first reported case of the use of monoclonal antibody factor IX in a patient with factor IX complex-induced disseminated intravascular coagulation.

引用

页码：621 / 622

页数：2

共 7 条

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CONLAN, MG
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[J]. AMERICAN JOURNAL OF HEMATOLOGY, 1990, 35 (03) : 203 - 207
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[7] MANNUCCI PM, 1990, BLOOD, V76, P2540

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