CHANGING CHARACTERISTICS OF AGING BIOFILMS

被引：4

作者：

ANWAR, H

STRAP, JL

机构：

[1] Department of Microbiology, University of Alberta, Edmonton

来源：

INTERNATIONAL BIODETERIORATION & BIODEGRADATION | 1992年 / 30卷 / 2-3期

关键词：

D O I：

10.1016/0964-8305(92)90062-S

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The use of an in-vitro chemostat system in the study of the interaction of young and aging biofilms with antibiotics is discussed. The study reveals that young biofilms are susceptible while aging biofilms are resistant to antibiotics. Possible physiological responses of bacteria in biofilms to the physical and chemical microenvironmental niches are used to illustrate the mechanisms of resistance of aging biofilms to antibiotics. It is the hope that this minireview will stimulate the development of effective strategies to eradicate aging biofilms.

引用

页码：177 / 186

页数：10

共 25 条

[1]

Anwar, Costerton, Enhanced activity of combination of tobramycin and piperacillin for eradication of sessile biofilm cells of Pseudomonas aeruginosa, Antimicrob. Agents Chemother., 34, pp. 1666-1671, (1990)

[2]

Anwar, Dasgupta, Lam, Costerton, Tobramycin resistance of mucoid Pseudomonas aeruginosa biofilm grown under iron limitation, J. Antimicrob. Chemother., 24, pp. 647-655, (1989)

[3]

Anwar, van Biesen, Dasgupta, Lam, Costerton, Interaction of biofilm bacteria with antibiotics in a novel in vitro chemostat system, Antimicrob. Agents Chemother., 33, pp. 1824-1826, (1989)

[4]

Anwar, Dasgupta, Costerton, Testing the susceptibility of bacteria in biofilms to antibacterials, Antimicrob. Agents Chemother., 34, pp. 2043-2046, (1990)

[5]

Anwar, Strap, Costerton, Growth characteristics and expression of iron-regulated outer membrane proteins of chemostat-grown biofilm cells of Pseudomonas aeruginosa, Can. J. Microbiol., 37, pp. 737-743, (1991)

[6]

Anwar, Strap, Costerton, Kinetic interaction of biofilm cells of Staphylococcus aureus with cephalexin and tobramycin in a chemostat system, Antimicrob. Agents Chemother., 36, pp. 890-893, (1992)

[7]

Anwar, Strap, Costerton, Dynamic interaction of biofilms of mucoid Pseudomonas aeruginosa with tobramycin and piperacillin, Antimicrob. Agents Chemother., 36, pp. 1208-1214, (1992)

[8]

Bullen, The significance of iron in infection, Rev. Infect. Dis., 3, pp. 1127-1137, (1981)

[9]

Costerton, Marrie, Cheng, Phenomena of bacterial adhesion, Bacterial Adhesion: Mechanisms and Physiological Significance, pp. 3-43, (1985)

[10]

Costerton, Cheng, Gessey, Ladd, Nickel, Dasgupta, Marrie, Bacterial biofilms in nature and disease, Ann. Rev. Microbiol., 41, pp. 435-464, (1987)

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