HLA-DR AND HLA-DQ GENOTYPING BY PCR-SSO IN SHANGHAI CHINESE

被引：30

作者：

WANG, FQ

SEMANA, G

FAUCHET, R

GENETET, B

机构：

[1] CTR REG TRANSFUS SANGUINE,HISTOCOMPATIBIL,RENNES,FRANCE

[2] CHR RENNES,HEMATOL LAB,RENNES,FRANCE

来源：

TISSUE ANTIGENS | 1993年 / 41卷 / 05期

关键词：

CHINESE; HLA CLASS-II; PCR; SSO;

D O I：

10.1111/j.1399-0039.1993.tb02010.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The polymorphism of HLA class II (HLA-DRB1, -DQA1 and -DQB1) were investigated in 89 Shanghai Han Chinese using polymerase-chain reaction amplification and oligonucleotide (PCR-SSO) typing. Of the 43 DRB1 alleles tested, 24 were observed. DRB1*0901 (16.85%), *0803 (9.55%), *1202 (9.55%) and *1501 (12.92%) were most frequent and account for the high frequencies of DR9, DR8, DR5 and DR2 specificities in this population. The alleles DRB1*0101, *0102 and *1001 had very low frequencies. Among the 8 DQA1 and 13 DQB1 alleles tested, only DQA1*0401 and DQB1*0402 were absent. DQA1*0301, and DQB1*0301 and *0303 were among the most common alleles of the two loci respectively. Unusual DRB1-DQA1-DQB1 haplotypes were observed and a DRB1 ''new'' allele was suggested.

引用

页码：223 / 226

页数：4

共 15 条

[1] NOMENCLATURE FOR FACTORS OF THE HLA SYSTEM, 1990 [J].

BODMER, JG ;

MARSH, SGE ;

ALBERT, ED ;

BODMER, WF ;

DUPONT, B ;

ERLICH, HA ;

MACH, B ;

MAYR, WR ;

PARHAM, P ;

SASAZUKI, T ;

SCHREUDER, GMT ;

STROMINGER, JL ;

SVEJGAARD, A ;

TERASAKI, PI .

TISSUE ANTIGENS, 1991, 37 (03) :97-104

[2] DNA TYPING FOR HLA-DR, HLA-DQ AND HLA-DP ALLELES IN A CHINESE POPULATION USING THE POLYMERASE CHAIN-REACTION (PCR) AND OLIGONUCLEOTIDE PROBES [J].

GAO, XJ ;

SUN, YP ;

AN, JB ;

FERNANDEZVINA, M ;

QOU, JN ;

LIN, L ;

STASTNY, P .

TISSUE ANTIGENS, 1991, 38 (01) :24-30

[3] STRUCTURE, FUNCTION, AND GENETICS OF HUMAN CLASS II MOLECULES [J].

GILES, RC ;

CAPRA, JD .

ADVANCES IN IMMUNOLOGY, 1985, 37 :1-71

[4] HUMAN CLASS-II MAJOR HISTOCOMPATIBILITY COMPLEX GENES AND PROTEINS [J].

KAPPES, D ;

STROMINGER, JL .

ANNUAL REVIEW OF BIOCHEMISTRY, 1988, 57 :991-1028

[5] THE POLYMORPHISM OF HLA ANTIGENS IN THE CHINESE [J].

LEE, TD ;

ZHAO, TM ;

MICKEY, R ;

SUN, YP ;

LEE, G ;

SONG, CX ;

CHENG, DZ ;

ZHOU, MS ;

DING, SQ ;

CHENG, DX ;

SONG, FJ ;

LEE, PY ;

AN, JB ;

MITTAL, KK .

TISSUE ANTIGENS, 1988, 32 (04) :188-208

[6]

LIAU SW, 1984, TISSUE ANTIGENS, V23, P308

[7] GENOTYPIC TYPING OF HLA CLASS-II - FROM THE BENCH TO THE BEDSIDE [J].

MACH, B ;

TIERCY, JM .

HUMAN IMMUNOLOGY, 1991, 30 (04) :278-284

[8]

MATTISU PL, HISTOCOMPATIBILITY T, P193

[9] HLA-DR GENE-FREQUENCIES IN THE JAPANESE POPULATION OBTAINED BY OLIGONUCLEOTIDE GENOTYPING [J].

OBATA, F ;

ITO, K ;

KANEKO, T ;

YANG, YG ;

ONDA, K ;

ITO, I ;

YABE, N ;

WATANABE, K ;

KASHIWAGI, N .

TISSUE ANTIGENS, 1991, 38 (03) :124-132

[10] SURVIVAL OF DNA HLA-DR TYPED AND MATCHED CADAVER KIDNEY-TRANSPLANTS [J].

OPELZ, G ;

MYTILINEOS, J ;

SCHERER, S ;

DUNCKLEY, H ;

TREJAUT, J ;

CHAPMAN, J ;

MIDDLETON, D ;

SAVAGE, D ;

FISCHER, O ;

BIGNON, JD ;

BENSA, JC ;

ALBERT, E ;

NOREEN, H .

LANCET, 1991, 338 (8765) :461-463

← 1 2 →