PULMONARY OBSTRUCTION IN INDIVIDUALS WITH CERVICAL SPINAL-CORD LESIONS UNMASKED BY BRONCHODILATOR ADMINISTRATION

被引：36

作者：

SPUNGEN, AM

DICPINIGAITIS, PV

ALMENOFF, PL

BAUMAN, WA

机构：

[1] Spinal Cord Damage Research Center, SCI and Medical Services Veterans Affairs Medical Center, Bronx, NY, 10468

[2] Division of Pulmonary/Critical Care Medicine, New York

来源：

PARAPLEGIA | 1993年 / 31卷 / 06期

关键词：

QUADRIPLEGIA; SPINAL CORD INJURY; PULMONARY OBSTRUCTION; VENTILATORY IMPAIRMENT; BRONCHODILATOR;

D O I：

10.1038/sc.1993.67

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In subjects with spinal cord injury (SCI) a restrictive ventilatory impairment has been well described. Despite numerous studies of pulmonary function in patients with SCI, evidence of an obstructive component of respiratory dysfunction as a result of paralysis has not been observed in this population. We performed spirometry in 34 patients with cervical SCI before and after administration of an inhaled bronchodilator. Significant improvement in flow rate was demonstrated in 14 (41%) subjects. Our results suggest that transection of the cervical spine may result in obstruction to air flow, possibly due to interruption of the sympathetic innervation of the lung with resultant unopposed parasympathetic tone producing bronchoconstriction.

引用

页码：404 / 407

页数：4

共 11 条

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