DETERMINATION OF THE DEGREE OF SUBSTITUTION OF HYDROXYPROPYLATED BETA-CYCLODEXTRINS BY DIFFERENTIAL SCANNING CALORIMETRY

被引：7

作者：

NOVAK, C ^{[1
]}

POKOL, G ^{[1
]}

SZTATISZ, J ^{[1
]}

SZENTE, L ^{[1
]}

SZEJTLI, J ^{[1
]}

机构：

[1] CYCLOLAB RES & DEV LTD,H-1525 BUDAPEST,HUNGARY

来源：

ANALYTICA CHIMICA ACTA | 1993年 / 282卷 / 02期

关键词：

THERMOMETRIC METHODS; CYCLODEXTRINS; DEGREE OF SUBSTITUTION; DIFFERENTIAL SCANNING CALORIMETRY; HYDROXYPROPYLATED BETA-CYCLODEXTRINS;

D O I：

10.1016/0003-2670(93)80216-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The general specifications of commercially available hydroxypropylated beta-cyclodextrins (HPBCDs) usually give information on the solubility, solubilizing potency and average degree of substitution (DS) of a given product. The DS value is regarded as suitable for quality control purposes. This paper describes a differential scanning calorimetric method to determine the DS, based on the fact that the glass temperature interval of the amorphous part of the sample depends on the degree of substitution of the HPBCD.

引用

页码：313 / 316

页数：4