ELECTRON MICROSCOPIC ANALYSIS OF HUMAN AMYLOID

被引：14

作者：

HIRSCHL, S

机构：

[1] Department of Pathology, Hospital for Joint Diseases, Medical Center, New York

来源：

JOURNAL OF ULTRASTRUCTURE RESEARCH | 1969年 / 29卷 / 3-4期

关键词：

D O I：

10.1016/S0022-5320(69)90107-5

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This study confirms that amyloid contains at least two distinct morphologic units, the ring and the filament. A method for obtaining both of these units in the same amyloid suspension is described. The two units are observed side by side, and their measurements are given. Both units are considered characteristic of the particulate amyloid, and their ratio is about 90-95 % filaments and 5-10 % rings. A model of the fibril ultrastructure is proposed. The effects of various purification methods on amyloid morphology are discussed. © 1969 Academic Press, Inc.

引用

页码：281 / &

共 22 条

[1]

BENDITT EP, 1967, FED PROC, V26, P300

[2]

BENDITT EP, 1968, 1967 P S AM GRON NET, P206

[3]

BESTETTI A, 1967, THESIS U ILLINOIS

[4] ULTRASTRUCTURE OF HUMAN AMYLOID AS REVEALED BY NEGATIVE STAINING TECHNIQUE [J].