NEUROMAGNETIC FIELDS IN MIGRAINE - PRELIMINARY FINDINGS

被引：31

作者：

BARKLEY, GL

TEPLEY, N

SIMKINS, R

MORAN, J

WELCH, KMA

机构：

[1] Department of Neurology, Henry Ford Hospital, Detroit, MI 48202

[2] Department of Physics, Oakland University, Rochester

来源：

CEPHALALGIA | 1990年 / 10卷 / 04期

关键词：

Magnetoencephalography; migraine; neuromagnetism; spreading cortical depression;

D O I：

10.1046/j.1468-2982.1990.1004171.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neuromagnetic signals consistent with spreading cortical depression have been observed in 9 of 12 migraine patients studied, but not in normal controls (out of 8 studied) or in patients with non-migrainous headache (4 studied). These signals consist of large amplitude, usually biphasic waveforms presumably arising from the onset or offset of spreading cortical depression in a sulcus, and prolonged attenuation of magnetic amplitudes, associated with suppressed neuronal activity. Techniques are described which recognize various kinds of artefacts and which distinguish changes in state of arousal of the patient from the presumed spreading cortical depression signals. © 1990, International Headache Society. All rights reserved.

引用

页码：171 / 176

页数：6

共 6 条

[1] Leao A.A.P., Spreading depression of activity in the cerebral cortex, J Neurophysiol, 7, pp. 379-390, (1944)
[2] Leao A.A.P., Morrison R.S., Propagation of spreading cortical depression, J Neurophysiol, 8, pp. 33-45, (1945)
[3] Milner P.M., Note on a possible correspondence between scotomas of migraine and spreading depression of Leao, Electroencephalogr Clin Neurophysiol, 10, (1958)
[4] Lashley K.S., Patterns of cerebral integration indicated by the scotomas of migraine, Arch Neurol Psychiat, 46, pp. 331-339, (1941)
[5] Lauritzen M., Cortical spreading depression as a putative migraine mechanism, Trends Neurosci, 10, pp. 8-13, (1987)
[6] Okada Y., Lauritzen M., Nicholson C., Magnetic field associated with spreading depression: a model for the detection of migraine, Brain Res, 442, pp. 185-190, (1988)

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