HUMAN CDNA-ENCODING DNAJ PROTEIN HOMOLOG

被引：62

作者：

OH, S

IWAHORI, A

KATO, S

机构：

[1] SAGAMI CHEM RES CTR,4-4-1 NISHI OHNUMA,SAGAMIHARA,KANAGAWA 229,JAPAN

[2] KANAGAWA ACAD SCI & TECHNOL,KANAGAWA,JAPAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1174卷 / 01期

关键词：

DNAJ; CDNA SEQUENCE; SEQUENCE COMPARISON; (HUMAN);

D O I：

10.1016/0167-4781(93)90104-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have cloned a cDNA encoding a DnaJ-like protein from the human fibrosarcoma HT-1080 cDNA library. This cDNA encodes a protein of 397 amino acid residues whose sequence shows 38.2% identity with the Escherichia coli DnaJ protein and 47.2% with the yeast DnaJ homologue along the entire length. Since the sequence contains the N-terminal domain region conserved in DnaJ family members and the four repeats of the Cys-X-X-Cys-X-Gly-X-Gly motif which are characteristic of DnaJ proteins we conclude that this cDNA clone encodes the human homologue of DnaJ.

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页码：114 / 116

页数：3

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