A NOVEL CYCLIN GENE (CCNF) IN THE REGION OF THE POLYCYSTIC KIDNEY-DISEASE GENE (PKD1)

被引：15

作者：

KRAUS, B

POHLSCHMIDT, M

LEUNG, ALS

GERMINO, GG

SNAREY, A

SCHNEIDER, MC

REEDERS, ST

FRISCHAUF, AM

机构：

[1] IMPERIAL CANC RES FUND,LONDON WC2A 3PX,ENGLAND

[2] JOHNS HOPKINS UNIV,SCH MED,DIV NEPHROL,BALTIMORE,MD 21205

[3] BRIGHAM & WOMENS HOSP,BOSTON,MA 02115

来源：

GENOMICS | 1994年 / 24卷 / 01期

关键词：

D O I：

10.1006/geno.1994.1578

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The major locus for autosomal dominant polycystic kidney disease (PKD1) is located in a gene-rich region on chromosome 16p13.3. Recently the identification of the gene responsible for PKD1 has been described. While searching for candidate genes in this region, we isolated a new member of the cyclin family. We have characterized the transcript by sequencing, determination of the exon intron boundaries, and Northern blot analysis. Cyclin F is related to A- and B-type cyclins by sequence, but its function is unknown. (C) 1994 Academic Press, Inc.

引用

页码：27 / 33

页数：7

共 41 条

[1]

[Anonymous], 1994, CELL, V77, P881

[2] CPG-RICH ISLANDS AND THE FUNCTION OF DNA METHYLATION [J].