METABOLISM OF LINDANE TO TETRACHLOROBENZENE

被引:17
作者
REED, WT
FORGASH, AJ
机构
[1] Department of Entomology, Economic Zoology, Rutgers-The State University, New Brunswick
关键词
D O I
10.1021/jf60164a048
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
In addition to the two previously reportedisomers of pentachlorocyclohexene, the 1,2,4,5-isomer of tetrachlorobenzene as a metabolite of lindane in susceptible and resistant strains of houseflies was tentatively identified. Products having retention times identical to those of 1,2,4- and 1,2,3-trichlorobenzene, 1,2,3,4-tetrachlorobenzene, and pentachlorobenzene were also formed. Application of γ-pentachlorocyclohexane produced only 1,2,4,5-tetrachlorobenzene and 1,2,4-trichlorobenzene, while application of the second isomer of PCCH yielded the five products. Treatment with 1,2,4-trichlorobenzene, 1,2,3,4-and 1,2,4,5-tetrachlorobenzene, or pentachlorobenzene produced no other organic-soluble materials. © 1969, American Chemical Society. All rights reserved.
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页码:896 / &
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