EFFECT OF DNA-BINDING ON INITIAL 8-METHOXYPSORALEN PHOTOCHEMISTRY

被引：29

作者：

GOYAL, GC

GROSSWEINER, LI

机构：

[1] Biophysics Laboratory, Physics Department, Illinois Institute of Technology, Chicago, Illinois

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 1979年 / 29卷 / 04期

关键词：

D O I：

10.1111/j.1751-1097.1979.tb07777.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Abstract—Flash photolysis experiments on the complex of 8‐methoxypsoralen with calf thymus DNA have shown binding promotes the anaerobic quenching of the 8‐MOP triplet state and inhibits the accessibility to oxygen. The results indicate dark psoralen‐DNA interactions suppress the singlet oxygen generation observed in prior work. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

收藏

页码：847 / 850

页数：4

相关论文

共 17 条

[1] POLARIZATION OF LUMINESCENCE OF PHENANTHRENE [J].

AZUMI, T ;

MCGLYNN, SP .

JOURNAL OF CHEMICAL PHYSICS, 1962, 37 (10) :2413-&

[2] RADIATION INACTIVATION OF T7 PHAGE [J].

BECKER, D ;

REDPATH, JL ;

GROSSWEINER, LI .

RADIATION RESEARCH, 1978, 73 (01) :51-74

[3] TRIPLET EXCITED-STATE OF FUROCOUMARINS - REACTION WITH NUCLEIC-ACID BASES AND AMINO-ACIDS [J].

BENSASSON, RV ;

LAND, EJ ;

SALET, C .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1978, 27 (03) :273-280

[4]

BLOK J, 1973, Current Topics in Radiation Research Quarterly, V9, P165

[5] ESR AND OPTICAL-ABSORPTION EVIDENCE FOR FREE-RADICAL INVOLVEMENT IN PHOTOSENSITIZING ACTION OF FUROCOUMARIN DERIVATIVES AND FOR THEIR SINGLET OXYGEN PRODUCTION [J].

CANNISTRARO, S ;

VANDEVORST, A .

BIOCHIMICA ET BIOPHYSICA ACTA, 1977, 476 (02) :166-177

[6] PHOTOREACTION BETWEEN FUROCOUMARINS AND VARIOUS DNA WITH DIFFERENT BASE COMPOSITIONS [J].

DALLACQUA, F ;

VEDALDI, D ;

RECHER, M .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1978, 27 (01) :33-36

[7]

DALLACQUA F, 1977, RES PHOTOBIOLOGY, P245

[8] EFFECT OF PARAMAGNETIC SPECIES ON 8-METHOXYPSORALEN-SENSITIZED PHOTOINACTIVATION OF BACTERIOPHAGE-LAMBDA [J].

FUJITA, H ;

KITAKAMI, M .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1977, 26 (06) :647-649

[9] THE BINDING OF ORGANIC IONS BY PROTEINS [J].

KLOTZ, IM ;

WALKER, FM ;

PIVAN, RB .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1946, 68 (08) :1486-1490

[10] A STUDY OF THE ADSORPTION OF DYES ON BOVINE SERUM ALBUMIN BY THE METHOD OF POLARIZATION OF FLUORESCENCE [J].

LAURENCE, DJR .

BIOCHEMICAL JOURNAL, 1952, 51 (02) :168-180