AUTOPSY STUDY OF CEREBROVASCULAR-DISEASE IN JAPANESE MEN WHO LIVED IN HIROSHIMA, JAPAN, AND HONOLULU, HAWAII

被引:44
作者
MITSUYAMA, Y
THOMPSON, LR
HAYASHI, T
LEE, KK
KEEHN, RJ
RESCH, JA
STEER, A
机构
[1] RADIAT EFFECTS RES FDN,DEPT EPIDEMIOL & STAT,HIROSHIMA,JAPAN
[2] KUAKINI MED CTR,DEPT PATHOL,HONOLULU,HI
[3] UNIV MINNESOTA,SCH MED,DEPT NEUROL,MINNEAPOLIS,MN 55455
关键词
D O I
10.1161/01.STR.10.4.389
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Evidence of cerebrovascular disease at autopsy was compared in 2 groups of men: 186 longtime residents of Hiroshima, Japan, and 253 men of Japanese ancestry long resident in Honolulu, Hawaii. They were 45 to 71 years-of-age at death. Atherosclerosis of the circle of Willis and its major branches, sclerosis of the intraparenchymal arteries and the frequency of cerebral hemorrhage and cerebral infarct were compared in the 2 populations. The Honolulu subjects had significantly more atherosclerosis of the circle of Willis, but less intraparenchymal artery sclerosis and less cerebral infarction. Cerebral hemorrhage was equally frequent in the 2 cities. It was concluded that cerebral infarction is more frequent in Japanese men in Hiroshima than Honolulu, and that men of Japanese ancestry in Honolulu are spared an appreciable risk of cerebral infarction through decreased frequency of intraparenchymal arterial sclerosis despite higher levels of atherosclerosis of large intracranial arteries. © 1979 American Heart Association, Inc.
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页码:389 / 395
页数:7
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