CONVULSIVE STATUS EPILEPTICUS IN CHILDREN

被引:42
作者
GROSSTSUR, V
SHINNAR, S
机构
[1] MONTEFIORE MED CTR,MONTEFIORE EINSTEIN EPILEPSY MANAGEMENT CTR,111 E 210TH ST,BRONX,NY 10467
[2] MONTEFIORE MED CTR,DEPT NEUROL,BRONX,NY 10467
[3] MONTEFIORE MED CTR,DEPT PEDIAT,BRONX,NY 10467
[4] YESHIVA UNIV ALBERT EINSTEIN COLL MED,BRONX,NY 10461
关键词
STATUS EPILEPTICUS; CHILDREN; ADOLESCENTS; EPIDEMIOLOGY; ELECTROENCEPHALOGRAPHY; EPILEPSY; FEBRILE SEIZURES; FOCAL EPILEPSY; GENERALIZED EPILEPSY; MORBIDITY; MORTALITY; EMERGENCY TREATMENT;
D O I
10.1111/j.1528-1157.1993.tb05901.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Status epilepticus (SE) occurs most commonly in infancy and childhood. Children with prior neurological abnormalities are most susceptible. More than 90% of cases are convulsive and the majority are generalized. SE may occur in the setting of an acute illness, in patients with established epilepsy or as a first unprovoked seizure. The etiology can be classified as idiopathic, remote symptomatic, febrile, acute symptomatic, or associated with a progressive encephalopathy. The morbidity and mortality of status have dramatically declined in recent years. Overall mortality in recent pediatric series was 3-10%, with almost all fatalities associated with acute central nervous system insults or progressive neurologic disorders. Neurological sequelae in children with idiopathic or febrile status are rare. Neurologically normal children with SE as their first unprovoked seizure have the same risk of experiencing subsequent seizures of any type as children who present with a brief first seizure. The risk of recurrent episodes of convulsive SE approaches 50% in neurologically abnormal children but is very low in neurologically normal children. The favorable outcome of SE in children may be related to advances in therapy and to the resistance of the immature brain to damage from seizures.
引用
收藏
页码:S12 / S20
页数:9
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