ALLYL PROTECTION IN THE SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDE PHOSPHOROTHIOATES

被引：9

作者：

HAYAKAWA, Y ^{[1
]}

HIROSE, M ^{[1
]}

NOYORI, R ^{[1
]}

机构：

[1] NAGOYA UNIV,FAC SCI,DEPT CHEM,CHIKUSA KU,NAGOYA 46401,JAPAN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1994年 / 13卷 / 6-7期

关键词：

D O I：

10.1080/15257779408012156

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Allyl and allyloxycarbonyl groups serve as useful protectors for internucleotide linkages and nucleoside bases, respectively, in the synthesis of partially or fully phosphorothioate-modified oligodeoxyribonucleotides.

引用

页码：1337 / 1345

页数：9

共 15 条

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[8] THE AUTOMATED SYNTHESIS OF SULFUR-CONTAINING OLIGODEOXYRIBONUCLEOTIDES USING 3H-1,2-BENZODITHIOL-3-ONE 1,1-DIOXIDE AS A SULFUR-TRANSFER REAGENT
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[10] PHOSPHOROTHIOATE ANALOGS OF OLIGODEOXYRIBONUCLEOTIDE - SYNTHESIS AND ACTIVITY AS INHIBITORS OF REPLICATION OF HUMAN-IMMUNODEFICIENCY-VIRUS
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