MECHANISM OF ACTION OF CERULENIN ON FATTY-ACID SYNTHETASE - EFFECT OF CERULENIN ON IODOACETAMIDE-INDUCED MALONYL-COA DECARBOXYLASE ACTIVITY

被引：70

作者：

KAWAGUCHI, A

TOMODA, H

NOZOE, S

OMURA, S

OKUDA, S

机构：

[1] TOHOKU UNIV,INST PHARMACEUT,SENDAI,MIYAGI 980,JAPAN

[2] KITASATO UNIV,KITASATO INST,MINATO KU,TOKYO 108,JAPAN

[3] KITASATO UNIV,SCH PHARMACEUT SCI,TOKYO 108,JAPAN

来源：

JOURNAL OF BIOCHEMISTRY | 1982年 / 92卷 / 01期

关键词：

D O I：

10.1093/oxfordjournals.jbchem.a133933

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：7 / 12

页数：6

共 11 条

[1] INHIBITION OF FATTY-ACID SYNTHESIS BY ANTIBIOTIC CERULENIN - SPECIFIC INACTIVATION OF BETA-KETOACYL-ACYL CARRIER PROTEIN SYNTHETASE [J].

DAGNOLO, G ;

ROSENFELD, IS ;

AWAYA, J ;

OMURA, S ;

VAGELOS, PR .

BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 326 (02) :155-166

[2] CERULENIN RESISTANCE IN A CERULENIN-PRODUCING FUNGUS - ISOLATION OF CERULENIN INSENSITIVE FATTY-ACID SYNTHETASE [J].

KAWAGUCHI, A ;

TOMODA, H ;

OKUDA, S ;

AWAYA, J ;

OMURA, S .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1979, 197 (01) :30-35

[3] REACTION OF YEAST FATTY-ACID SYNTHETASE WITH IODOACETAMIDE .2. IDENTIFICATION OF AMINO-ACID RESIDUES REACTING WITH IODOACETAMIDE AND PRIMARY STRUCTURE OF A PEPTIDE CONTAINING PERIPHERAL SULFHYDRYL-GROUP [J].

KRESZE, GB ;

STEBER, L ;

LYNEN, F ;

OESTERHELT, D .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 79 (01) :181-190

[4] REACTION OF YEAST FATTY-ACID SYNTHETASE WITH IODOACETAMIDE .3. MALONYL-COENZYME-A DECARBOXYLASE AS PRODUCT OF REACTION OF FATTY-ACID SYNTHETASE WITH IODOACETAMIDE [J].

KRESZE, GB ;

STEBER, L ;

LYNEN, F ;

OESTERHELT, D .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 79 (01) :191-199

[5]

LYNEN F, 1980, EUR J BIOCHEM, V112, P431

[6] REACTION OF YEAST FATTY-ACID SYNTHETASE WITH IODOACETAMIDE .1. KINETICS OF INACTIVATION AND EXTENT OF CARBOXAMIDOMETHYLATION [J].

OESTERHELT, D ;

BAUER, H ;

KRESZE, GB ;

STEBER, L ;

LYNEN, F .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 79 (01) :173-180

[7]

Omura S, 1981, Methods Enzymol, V72, P520

[8] PANTETHEINE-FREE MUTANTS OF YEAST FATTY-ACID-SYNTHETASE COMPLEX [J].

SCHWEIZER, E ;

KNIEP, B ;

CASTORPH, H ;

HOLZNER, U .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 39 (02) :353-362

[9] MALONYL BOND POSITIONS OF FATTY ACID SYNTHETASE COMPLEX OF YEAST [J].

SCHWEIZER, E ;

PICCININI, F ;

DUBA, C ;

GUNTHER, S ;

RITTER, E ;

LYNEN, F .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1970, 15 (03) :483-+

[10]

STOOPS JK, 1981, J BIOL CHEM, V256, P8364

← 1 2 →